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hot product/top quality raw material amantadine hcl Amantadine HCl hot product/top quality raw material amantadine hcl Amantadine HCl hot product/top quality raw material amantadine hcl Amantadine HCl

hot product/top quality raw material amantadine hcl Amantadine HCl

can automatically finish raw materials preparation, extrusion, shaping, cutting, drying and flavoring at a time.hot product/top quality raw material amantadine hcl Amantadine...
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Product Description

can automatically finish raw materials preparation, extrusion, shaping, cutting, drying and flavoring at a time.hot product/top quality raw material amantadine hcl Amantadine HCl has the advantages of more machines choice, flexible and diverse configurations, wide range of raw materials application, numerous in products variety and easy opration. hot product/top quality raw material amantadine hcl Amantadine HCl can make the puffed snacks, corn bars, corn sticks and so on. After being puffed by , the products are crispy, easy to digest and unique taste. They are the perfect leisure food for hot product/top quality raw material amantadine hcl Amantadine HCl consumers.

of hot product/top quality raw material amantadine hcl Amantadine HCl comprises of U-shape barrel,transmisstion parts and ribbon agitating blades usually have doubleor triple layers with outside screw gathering material from side to center and inside screw transmitting the material from center of hot product/top quality raw material amantadine hcl Amantadine HCl to sides to form convection mix.hot product/top quality raw material amantadine hcl Amantadine HCl has a very good effect for mixing spice or dry powder with liquid.

comes from defatted soy flour, which is a by-product of soybean oil, so it is plentiful in supply. hot product/top quality raw material amantadine hcl Amantadine HCl is also quick to cook and a great source of vegetable protein without all the fat.hot product/top quality raw material amantadine hcl Amantadine HCl uses the newest production equipments. are researched and developed according to the market demand and basing on the advanced equipments. Jinan Joysun Machinery Co., Ltd. hot product/top quality raw material amantadine hcl Amantadine HCl has become the serialization and many kinds of collocations can meet the different customer's needs.

 Product Description

DESCRIPTION

Amantadine hydrochloride is designated chemically as 1-adamantanamine hydrochloride.Amantadine hydrochloride is a stable white or nearly white crystalline powder, freely soluble in water and soluble in alcohol and in chloroform.Amantadine hydrochloride has pharmacological actions as both an anti-Parkinson and an antiviral drug.Each tablet intended for oral administration contains 100 mg amantadine hydrochloride and has the following inactive ingredients: microcrystalline cellulose, povidone, sodium starch glycolate, magnesium stearate, colloidal silicon dioxide, FD&C Yellow No. 6 Aluminum Lake.

CLINICAL PHARMACOLOGY

Pharmacodynamics

Mechanism of Action: Antiviral The mechanism by which amantadine exerts its antiviral activity is not clearly understood. It appears to mainly prevent the release of infectious viral nucleic acid into the host cell by interfering with the function of the transmembrane domain of the viral M2 protein. In certain cases, amantadine is also known to prevent virus assembly during virus replication. It does not appear to interfere with the immunogenicity of inactivated infhot product/top quality raw material amantadine hcl Amantadine HClza A virus vaccine.

Antiviral Activity: Amantadine inhibits the replication of infhot product/top quality raw material amantadine hcl Amantadine HClza A virus isolates from each of the subtypes, i.e., H1N1, H2N2 and H3N2. It has very little or no activity against infhot product/top quality raw material amantadine hcl Amantadine HClza B virus isolates. A quantitative relationship between the in vitro susceptibility of infhot product/top quality raw material amantadine hcl Amantadine HClza A virus to amantadine and the clinical response to therapy has not been established in man. Sensitivity test results, expressed as the concentration of amantadine required to inhibit by 50% the growth of virus (ED50) in tissue culture vary greatly (from 0.1 μg/mL to 25.0 μg/mL) depending upon the assay protocol used, size of virus inoculum, isolates of infhot product/top quality raw material amantadine hcl Amantadine HClza A virus strains tested, and the cell type used. Host cells in tissue culture readily tolerated amantadine up to a concentration of 100 μg/mL.

Drug Resistance: Infhot product/top quality raw material amantadine hcl Amantadine HClza A variants with reduced in vitro sensitivity to amantadine have been isolated from epidemic strains in areas where adamantane derivatives are being used. Infhot product/top quality raw material amantadine hcl Amantadine HClza viruses with reduced in vitro sensitivity have been shown to be transmissible and to cause typical infhot product/top quality raw material amantadine hcl Amantadine HClza illness. The quantitative relationship between the in vitro sensitivity of infhot product/top quality raw material amantadine hcl Amantadine HClza A variants to amantadine and the clinical response to therapy has not been established.

Mechanism of Action: Parkinson's Disease The mechanism of action of amantadine in the treatment of Parkinson's disease and drug-induced extrapyramidal reactions is not known. Data from earlier animal studies suggest that amantadine may have direct and indirect effects on dopamine neurons. More recent studies have demonstrated that amantadine is a weak, non-competitive NMDA receptor antagonist (K1 = 10μM). Although amantadine has not been shown to possess direct anticholinergic activity in animal studies, clinically, it exhibits anticholinergic-like side effects such as dry mouth, urinary retention, and constipation.

Specifications

amantadine hcl CAS 665-66-7 1.standard:USP32 USP30 2.competitive price and top quality 3.prompt delivery 4.zhejiang

hot product/top quality raw material amantadine hcl CAS 665-66-7 China manufactuer

hot product/top quality raw material amantadine hcl CAS 665-66-7 China manufactuer Company Description:

Our company specializes in the R&D, manufacture and marketing of Active Pharmaceutical Ingredients, Veterinary Products and Fine Chemical Intermediates.

Based on advanced technologies, fine synthetic & analytical equipment and environmentally friendly facilities, our plants have the ability to produce various products and intermediates. We have won the title of "Reliable Partner of Contract Manufacturing Business".

"Ideas for health and service" is our commitment. We are ready to be your win-win partner.

amamtadine hcl Our advantages:

1.Marketing and sales partner to hot product/top quality raw material amantadine hcl Amantadine HCl suppliers of feed and veterinarian additives and ingredients.

2.A broad range of high quality products, manufactured by hot product/top quality raw material amantadine hcl Amantadine HCl producers, and supported with outstanding quality control systems.

3. 15 years of experience, resulting in a solid reputation in the global animal health and nutrition industry.

4.Professional and outstanding logistic expertise.

5. Proven state of the art service and reliability.

6.Highly skilled scientific and technical staff, assuming product and market development, and guaranteeing optimal support to customers and suppliers on promotion, registration, marketing and sales.

7.Competence for product and concept development, hot product/top quality raw material amantadine hcl Amantadine HCl to the introduction of innovative feed additives on a global level.

amamtadine hcl Specifications

amantadine hcl Product Name

amantadine hcl

amantadine hcl Properties

white crystal powder, odourless; soluble in water, ethanol and chloroform, unsoluble in theacetone

amantadine hcl Package

25kg/drum

amantadine hcl Cas Number

665-66-7

amantadine hcl MF

C10H15NH2HCl

amantadine hcl MW

187.71

amantadine hcl Brand Name

VEGA

amantadine hcl Purity

98%-102% min

amantadine hcl Piace of orign

Zhejiang,China

amantadine hcl Storage&Transportation

Store in a tightly closed container. Store in a cool, dry,well-ventilated area away from incompatible substances.Avoid to contact water or moisture during Storing&Transporting

amantadine hcl Usage

Use to make intermediate of antivirus mediclne for treating A2 type flu virus, Has antipyretic effect in the clinical pharmacology;Amend fremitus and anaesthesia of Parkinson's disease symptom.

For a variety of inflammation, septicemia, viral pneumonia and antibiotics antifebrile action. Primary tremor palsyand encephalitis, after cerebral arteriosclerosis of tremorparalysis syndrome,

prevention and treatment of infhot product/top quality raw material amantadine hcl Amantadine HClza A viruses

Packaging & Shipping

Our normal packaging is 25kg/drum or box.

The shipping term can be by sea, by air, your other express company like DHL, FEDEX, EMS, and TNT. Our Services

a) Free sample can be supplied.

b) Guide our clients by professinal techniques and teach them how to use our product after sales

c) Define lowest price on quality products.

Company Information

Introduction

Shaanxi Top Pharm Chemical Co., Ltd. has been primarily engaged in the research, development,

and marketing of various photochemical products since 1999.

We take full advantages of natural pharmaceutical resources which grow in the areas of Qinba Mountain and Qinling Mountain.

Within years' development, our core competitiveness has been firmly formed and developed.

At Top Pharm, we devoted ourselves to the sophisticated products with carefully selected natural resources to

meet the demands' of our customers in advance.

Our detailed business scope:

1. Extract/sap and separated effective components from natural plants
Our production procedures are strictly limited to the stainless and sterile steps, together with our advanced technology,

which ensures guaranteed quality and superior service.

2. Supplying amino acid/aminophenol & vitamin series of products
We supply a wide range of amino element together with the natural and synthetic vitamin products which are essential to human bodies.

3. Identifying the quality of medicine raw materials
We guarantee that every product we provide for you is through effective component analysis.

4. Developing the hot product/top quality raw material amantadine hcl Amantadine HCl pharmaceutical intermediates
We supply products with the hot product/top quality raw material amantadine hcl Amantadine HCl marketing reports.

5. Providing functional ingredients
We manufacture healthy and high-level functional food ingredients, such as phytosterol, sitosterol, and plant ester.

At Top Pharm, we firmly believe that customers' success is our success.

Each staff member of our company is devoted to being ready for your requirements.

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